منابع مشابه
Halothane hepatotoxicity and the reduced derivative, 1,1,1-trifluoro-2-chloroethane.
Halothane (1,1,1-trifluoro-2-bromo-2-chloroethane) is a safe, clinically useful inhalation anesthetic. Rare, unpredictable cases of liver necrosis have been reported following its use. Although the mechanism of this reaction in man is unknown the most plausible is biotransformation to reactive intermediates compounds. The oxidative metabolism of halothane appears to be benign. There is early ev...
متن کاملHalothane macrophage migration inhibtiion factor test in halothane-associated hepatitis.
As an index of delayed hypersensitivity in vitro halothane macrophage migration inhibition factor tests (halothane-MIF tests) were performed on peripheral blood lymphocytes from five patients with halothane hepatitis. Twenty-two subjects exposed to halothane, but with no evidence of jaundice, five 'healthy' hospital anaesthetists, nine jaundiced subjects without halothane exposure, and 10 healt...
متن کاملPost-halothane jaundice in relation to previous administration of halothane.
The time interval since previous anaesthesia was compared in a surgical population in South Wales and in patients who developed jaundice after halothane. There was a significant difference in the pattern of time interval since previous general anaesthetics in the surgical population and in those patients who developed jaundice after halothane. In the group who developed jaundice there was an "e...
متن کاملISOFLURANE VERSUS HALOTHANE Physical properties of Isoflurane compared to Halothane
Isoflurane is a haloginated ether, is stable when stored and is presented as 99.9% pure product. The absence of a preservative make vaporisation more efficient and it is very unlikely that moving parts of the vaporiser will stick. The physical properties of isoflurane are similar to those of halothane. The minimum alveolar concentration (MAC) of isoflurane in the different target species is det...
متن کاملHalothane anaesthesia in turkeys.
An anaesthetic technique employing halothane in oxygen for use in adult turkeys is described. The mixture was administered using a Magill attachment and a Hall cat mask. Induction was rapid and excitement-free. Anaesthesia was maintained for varying periods of time up to a maYimnm of 80 minutes. Recovery was rapid. In a total of twenty-five turkeys no deaths occurred which were attributable to ...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1973
ISSN: 0035-9157
DOI: 10.1177/00359157730661p130